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Prilocaine base and lidocaine base are both relatively hydrophilic amino-amides. The mean (±SD) prilocaine Cmax was 106 (±45) ng/mL, ranging between 53 and 181 ng/mL. lidocaine and prilocaine helps prevent pain, but it will not calm a frightened child. 5% is a microemulsion in which the oil phase is a eutectic mixture of lidocaine and prilocaine in a ratio of 1:1 by weight. Prilocaine is chemically designated as N-(2-methylphenyl)-2 (propylamino)-propanamide and has an octanol:water partition ratio of 25 at pH 7.

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